Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 2/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303064 | 0.82 | PTAFR (0.52) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9302805 | 0.81 | TNF (0.53) | PTAFRGALR3NR2F2RAB9AAGTR1 | |
| SCHEMBL9302266 | 0.79 | PTAFR (0.55) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9302451 | 0.79 | AGTR2 (0.47) | PTAFRGALR3NR2F2RAB9AAGTR1 | |
| SCHEMBL9302296 | 0.77 | PTAFR (0.52) | PTAFRGALR3NR2F2RAB9AAGTR1 | |
| SCHEMBL8560863 | 0.76 | GALR3 (0.50) | PTAFRGALR3NR2F2RAB9AAGTR1 | |
| SCHEMBL8567343 | 0.75 | GALR3 (0.48) | PTAFRGALR3NR2F2RAB9AAGTR1 | |
| SCHEMBL9303050 | 0.73 | PTAFR (0.59) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL8127579 | 0.72 | HDAC1 (0.51) | PTAFRGALR3NR2F2RAB9AAGTR1 | |
| SCHEMBL9302155 | 0.72 | PTAFR (0.58) | PTAFRGALR3NR2F2RAB9ATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |