Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 2/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303064 | 0.82 | PTAFR (0.52) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL9302266 | 0.80 | PTAFR (0.55) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL9303050 | 0.77 | PTAFR (0.59) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL9301901 | 0.77 | PTAFR (0.47) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL9302155 | 0.76 | PTAFR (0.58) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL8129273 | 0.76 | PTAFR (0.52) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL9303746 | 0.75 | PTAFR (0.67) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL8137319 | 0.75 | HDAC1 (0.56) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL8123854 | 0.75 | PTAFR (0.47) | PTAFRHDAC1HDAC6GALR3NR2F2 | |
| SCHEMBL8137536 | 0.74 | TNF (0.59) | PTAFRHDAC1HDAC6GALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |