Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301193 | 0.80 | FDPS (0.53) | FDPS | |
| SCHEMBL21886609 | 0.75 | HRH3 (0.35) | — | |
| SCHEMBL762417 | 0.75 | FDPS (0.56) | FDPS | |
| SCHEMBL9301189 | 0.73 | FDPS (0.58) | FDPS | |
| SCHEMBL9302201 | 0.73 | FDPS (0.59) | FDPS | |
| SCHEMBL9300273 | 0.73 | FDPS (0.64) | FDPS | |
| SCHEMBL9301543 | 0.70 | FDPS (0.59) | FDPS | |
| SCHEMBL9300487 | 0.68 | FDPS (0.63) | FDPS | |
| SCHEMBL15316686 | 0.67 | CYP2D6 (0.37) | — | |
| SCHEMBL9302739 | 0.67 | FDPS (0.56) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |