Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 7/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301443 | 0.85 | CXCR4 (0.65) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9303177 | 0.81 | CXCR4 (0.60) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9302160 | 0.78 | DRD2 (0.48) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9301871 | 0.75 | CXCR4 (0.61) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9301885 | 0.75 | CXCR4 (0.56) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL13140415 | 0.75 | CXCR4 (0.70) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL14492265 | 0.72 | CXCR4 (0.62) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9303150 | 0.71 | ADRA1D (0.59) | CXCR4 | |
| SCHEMBL14492263 | 0.70 | CXCR4 (0.59) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL6524716 | 0.70 | CXCR4 (0.58) | CXCR4DRD4DRD2ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |