Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 7/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303150 | 0.86 | ADRA1D (0.59) | CXCR4 | |
| SCHEMBL9301443 | 0.82 | CXCR4 (0.65) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9301885 | 0.81 | CXCR4 (0.56) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL13140415 | 0.79 | CXCR4 (0.70) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9302740 | 0.79 | EPHX2 (0.53) | LMNAMEN1KMT2A | |
| SCHEMBL9303177 | 0.79 | CXCR4 (0.60) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL14492265 | 0.76 | CXCR4 (0.62) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9302163 | 0.75 | CXCR4 (0.56) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL27895731 | 0.74 | ACHE (0.59) | CXCR4DRD4DRD2ACHEBACE1 | |
| SCHEMBL9301861 | 0.74 | BACE1 (0.49) | CXCR4DRD4DRD2ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |