SCHEMBL930222

SCHEMBL930222

CC1(c2ccccc2C2CCCCC2)CCCC1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.43
PTGS2 P35354 1/20 0.39
PDK2 Q15119 1/20 0.38
PDK4 Q16654 1/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CHRNA7 P36544 1/20 0.37
OPRL1 P41146 1/20 0.37
TRPA1 O75762 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27533686 1.00 PRCP (0.43) PRCPPTGS2PDK2PDK4GAA
SCHEMBL28259692 0.85 HTR2C (0.46) PRCPPTGS2
SCHEMBL11804925 0.78 SLC6A2 (0.39)
SCHEMBL10418115 0.75 AKR1C1 (0.51) PRCPGAASMN1; SMN2PTGDR2
SCHEMBL3480987 0.73 HTR1D (0.39) PRCPGAASMN1; SMN2OPRL1PTGDR2
SCHEMBL42781 0.73 PTGDR2 (0.48) PRCPPTGS2PTGDR2
Benzene SCHEMBL27853973 0.71 PTGDR2 (0.52) PTGS2PTGDR2
SCHEMBL2213384 0.71 RARB (0.42) SMN1; SMN2
SCHEMBL6152617 0.71 HDAC4 (0.49) SMN1; SMN2OPRL1
SCHEMBL779938 0.71 CHRNB4 (0.46) PTGS2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2297071-B1 PROCESS FOR PRODUCING CYCLOHEXYLBENZENE EXXONMOBIL CHEM PATENTS INC (US) 2016-03-30 EP claimed
US-8329956-B2 Process for producing cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-12-11 US claimed
US-20120178969-A1 Process For Producing Cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. 2012-07-12 US claimed
US-8178728-B2 Process for producing cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-05-15 US claimed
EP-2297071-A1 PROCESS FOR PRODUCING CYCLOHEXYLBENZENE ExxonMobil Chemical Patents Inc. (US) 2011-03-23 EP claimed
US-20110015457-A1 Process for Producing Cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. 2011-01-20 US claimed
WO-2009128984-A1 PROCESS FOR PRODUCING CYCLOHEXYLBENZENE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-10-22 WO claimed
US-11779914-B2 Hydroalkylation of mononuclear aromatic hydrocarbons to mono cycloalkyl aromatic hydrocarbons BHARAT PETROLEUM CORPORATION LIMITED (IN) 2023-10-10 US disclosed
US-20220088582-A1 HYDROALKYLATION OF MONONUCLEAR AROMATIC HYDROCARBONS TO MONO CYCLOALKYL AROMATIC HYDROCARBONS INDIAN INSTITUTE OF TECHNOLOGY DELHI (IN) 2022-03-24 US disclosed
EP-2297071-B1 PROCESS FOR PRODUCING CYCLOHEXYLBENZENE EXXONMOBIL CHEM PATENTS INC (US) 2016-03-30 EP disclosed
US-8329956-B2 Process for producing cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-12-11 US disclosed
US-20120178969-A1 Process For Producing Cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. 2012-07-12 US disclosed
US-8178728-B2 Process for producing cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-05-15 US disclosed
EP-2297071-A1 PROCESS FOR PRODUCING CYCLOHEXYLBENZENE ExxonMobil Chemical Patents Inc. (US) 2011-03-23 EP disclosed
US-20110015457-A1 Process for Producing Cyclohexylbenzene EXXONMOBIL CHEMICAL PATENTS INC. 2011-01-20 US disclosed
WO-2009128984-A1 PROCESS FOR PRODUCING CYCLOHEXYLBENZENE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-10-22 WO disclosed
US-3962362-A HYDROALKYLATION, DEHYDROGENATION TEXACO DEVELOPMENT CORPORATION (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220088582-A1 HYDROALKYLATION OF MONONUCLEAR AROMATIC HYDROCARBONS TO MONO CYCLOALKYL AROMATIC HYDROCARBONS AHR, HAMP, HCCS PRCP 2933/4885PTGS2 4203/4885PDK2 2644/4885
US-11779914-B2 Hydroalkylation of mononuclear aromatic hydrocarbons to mono cycloalkyl aromatic hydrocarbons AHR, HAMP, HCCS PRCP 2933/4885PTGS2 4203/4885PDK2 2644/4885
US-20110015457-A1 Process for Producing Cyclohexylbenzene MCM2, MCM4, MCM6 PRCP 3239/4885PTGS2 276/4885PDK2 2476/4885
US-20120178969-A1 Process For Producing Cyclohexylbenzene MCM2, MCM4, MCM6 PRCP 3239/4885PTGS2 276/4885PDK2 2476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.