Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 11/20 | 0.41 |
| ▸ | USP7 | Q93009 | 9/20 | 0.38 |
| ▸ | USP47 | Q96K76 | 4/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302326 | 0.78 | S100A4 (0.47) | USP8USP7USP47MAOB | |
| SCHEMBL9302270 | 0.75 | CCR1 (0.33) | MAOB | |
| SCHEMBL9301263 | 0.74 | CCR1 (0.33) | MAOB | |
| SCHEMBL9302208 | 0.72 | TDP1 (0.55) | — | |
| SCHEMBL29117498 | 0.69 | ELANE (0.55) | USP8USP7MAOB | |
| SCHEMBL9849269 | 0.68 | ELANE (0.53) | USP8USP7 | |
| SCHEMBL9302015 | 0.66 | GAA (0.55) | — | |
| SCHEMBL30540213 | 0.66 | USP8 (0.61) | USP8USP7USP47EGLN2 | |
| SCHEMBL26635265 | 0.66 | USP8 (0.61) | USP8USP7USP47EGLN2 | |
| SCHEMBL8975796 | 0.64 | DDB1 (0.34) | NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |