Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301587 | 0.92 | CCKBR (0.57) | CCKBRCYSLTR1CYSLTR2MEN1NPC1 | |
| SCHEMBL9301937 | 0.90 | CCKBR (0.55) | CCKBRCYSLTR1CCKARBACE1BACE2 | |
| SCHEMBL9303126 | 0.90 | CCKBR (0.55) | CCKBRCYSLTR1CCKARBACE1BACE2 | |
| SCHEMBL9702299 | 0.87 | CCKBR (0.55) | CCKBRCCKARBACE1BACE2 | |
| SCHEMBL9701161 | 0.87 | CCKBR (0.55) | CCKBRCCKARBACE1BACE2 | |
| SCHEMBL9303570 | 0.82 | CCKBR (0.45) | CCKBRCYSLTR1CYSLTR2MEN1POLB | |
| SCHEMBL9699961 | 0.79 | CCKBR (0.45) | CCKBRSMN1; SMN2BACE1BACE2 | |
| SCHEMBL9699964 | 0.79 | CCKBR (0.45) | CCKBRSMN1; SMN2BACE1BACE2 | |
| SCHEMBL9301948 | 0.77 | CCKBR (0.41) | CCKBRNPC1RAB9ACCKARBACE1 | |
| SCHEMBL9218194 | 0.76 | CCKBR (0.35) | CCKBRCCKARBACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |