Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301948 | 0.91 | CCKBR (0.41) | CCKBRATAD2ALDH1A1 | |
| SCHEMBL9301587 | 0.90 | CCKBR (0.57) | CCKBRCYSLTR1EPHX2PPARGCYSLTR2 | |
| SCHEMBL9302356 | 0.82 | CCKBR (0.48) | CCKBRCYSLTR1EPHX2PPARGCYSLTR2 | |
| SCHEMBL9303126 | 0.80 | CCKBR (0.55) | CCKBRCYSLTR1EPHX2PPARGEGFR | |
| SCHEMBL9301937 | 0.80 | CCKBR (0.55) | CCKBRCYSLTR1EPHX2PPARGEGFR | |
| SCHEMBL9699964 | 0.79 | CCKBR (0.45) | CCKBRMAPTMAPK1ALDH1A1 | |
| SCHEMBL9701161 | 0.77 | CCKBR (0.55) | CCKBR | |
| SCHEMBL9702299 | 0.77 | CCKBR (0.55) | CCKBR | |
| SCHEMBL9545602 | 0.75 | CCKBR (0.42) | CCKBRMAPTMAPK14ALDH1A1 | |
| SCHEMBL9545574 | 0.74 | CCKBR (0.43) | CCKBRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |