Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.46 |
| ▸ | FABP3 | P05413 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301099 | 0.74 | FABP3 (0.48) | FABP4FABP5FABP3CYP2C9KDM4E | |
| SCHEMBL9302519 | 0.70 | ADORA2A (0.43) | KDM4ESMN1; SMN2MAPTHTT | |
| SCHEMBL8956235 | 0.67 | DHODH (0.49) | FABP4FABP5FABP3CYP2C9KDM4E | |
| SCHEMBL9302391 | 0.65 | APP (0.42) | KDM4ELMNASMN1; SMN2MAPTDHODH | |
| SCHEMBL8956575 | 0.65 | DHODH (0.58) | FABP4FABP3KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8956069 | 0.64 | LMNA (0.51) | FABP4FABP5FABP3KDM4ELMNA | |
| SCHEMBL8703691 | 0.64 | ACP1 (0.41) | LMNASMN1; SMN2MAPTDHODHHTT | |
| SCHEMBL14917093 | 0.64 | FABP4 (1.00) | FABP4FABP5FABP3CYP2C9KDM4E | |
| SCHEMBL8956209 | 0.63 | LMNA (0.56) | FABP4FABP3CYP2C9KDM4ELMNA | |
| SCHEMBL14544897 | 0.61 | GCGR (0.44) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369109-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-11-29 | — | — | US | disclosed |