Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 3/20 | 0.48 |
| ▸ | FABP4 | P15090 | 3/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MAT2A | P31153 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703691 | 0.82 | ACP1 (0.41) | HTTALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL9302376 | 0.74 | FABP4 (0.46) | FABP3FABP4FABP5MAPK1HTT | |
| SCHEMBL9302519 | 0.72 | ADORA2A (0.43) | HTTALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL9302391 | 0.72 | APP (0.42) | MAPK1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3486575 | 0.67 | KDM4E (0.71) | MAPK1ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL13585806 | 0.66 | KDM4E (0.58) | FABP3FABP4FABP5MAPK1ALDH1A1 | |
| SCHEMBL14951901 | 0.65 | MAOA (0.55) | FABP3FABP4HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL14917093 | 0.65 | FABP4 (1.00) | FABP3FABP4FABP5MAPK1HTT | |
| SCHEMBL28883104 | 0.65 | MAPK1 (0.61) | FABP3FABP4MAPK1HTTNPC1 | |
| SCHEMBL3321035 | 0.64 | FABP4 (0.62) | FABP3FABP4FABP5MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369109-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-11-29 | — | — | US | claimed |
| EP-0475627-B1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEM RES (JP) | 1994-10-19 | — | — | EP | claimed |
| US-5276154-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-04 | — | — | US | claimed |
| EP-0475627-B1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEM RES (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5276154-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0475627-A1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-03-18 | — | — | EP | disclosed |