Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | NOS3 | P29474 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15073401 | 0.91 | NOS3 (0.52) | NOS3NOS2MEN1KMT2AKDM4E | |
| SCHEMBL9349552 | 0.89 | ESR2 (0.60) | ESR1ESR2NOS3NOS2MEN1 | |
| SCHEMBL1890792 | 0.87 | NOS3 (0.58) | ESR1ESR2NOS3MEN1KMT2A | |
| SCHEMBL1890790 | 0.87 | NOS3 (0.58) | ESR1ESR2NOS3MEN1KMT2A | |
| SCHEMBL8155649 | 0.87 | NOS3 (0.58) | ESR1ESR2NOS3MEN1KMT2A | |
| SCHEMBL11421052 | 0.83 | CYP2D6 (0.53) | ESR2NOS3MEN1KMT2ANPC1 | |
| SCHEMBL11421050 | 0.83 | CYP2D6 (0.53) | ESR2NOS3MEN1KMT2ANPC1 | |
| SCHEMBL16382908 | 0.83 | CYP2D6 (0.53) | ESR2NOS3MEN1KMT2ANPC1 | |
| SCHEMBL15143942 | 0.82 | NOS1 (0.55) | ESR1ESR2NOS3MEN1KMT2A | |
| SCHEMBL15137058 | 0.82 | NOS1 (0.55) | ESR1ESR2NOS3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| WO-1993014053-A1 | PROCESS FOR THE PREPARATION OF 1,3,5-TRIS(4'-HYDROXYARYL)BENZENE | HOECHST CELANESE CORPORATION (US) | 1993-07-22 | — | — | WO | claimed |
| US-5344980-A | Process for the preparation of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORP. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5344980-A | Process for the preparation of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORP. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1993014053-A1 | PROCESS FOR THE PREPARATION OF 1,3,5-TRIS(4'-HYDROXYARYL)BENZENE | HOECHST CELANESE CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |
| WO-1993014053-A1 | PROCESS FOR THE PREPARATION OF 1,3,5-TRIS(4'-HYDROXYARYL)BENZENE | HOECHST CELANESE CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |