Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | PTAFR | P25105 | 1/20 | 0.57 |
| ▸ | GALR3 | O60755 | 2/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302639 | 0.85 | PTAFR (0.64) | TNFPTAFRGALR3NR2F2RAB9A | |
| SCHEMBL9303788 | 0.83 | TNF (0.61) | CNR2TNFPTAFRGALR3NR2F2 | |
| SCHEMBL9302593 | 0.81 | PTAFR (0.62) | TNFPTAFRGALR3NR2F2RAB9A | |
| SCHEMBL9302023 | 0.79 | PTAFR (0.66) | TNFPTAFRGALR3NR2F2RAB9A | |
| SCHEMBL9302294 | 0.79 | GALR3 (0.67) | TNFPTAFRGALR3NR2F2RAB9A | |
| SCHEMBL9302731 | 0.78 | GALR3 (0.68) | TNFPTAFRGALR3NR2F2RAB9A | |
| SCHEMBL9299436 | 0.78 | PTAFR (0.58) | TNFPTAFRGALR3NR2F2RAB9A | |
| SCHEMBL9299088 | 0.77 | PTAFR (0.62) | TNFPTAFRGALR3NR2F2RAB9A | |
| SCHEMBL231295 | 0.76 | TNF (1.00) | TNFGALR3NR2F2RAB9AMEN1 | |
| SCHEMBL9300543 | 0.76 | TNF (0.67) | TNFPTAFRGALR3NR2F2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |