SCHEMBL9302644

SCHEMBL9302644

CON(C)C(=O)/C=C/c1ccc(C)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 4/20 0.58
MAPT P10636 6/20 0.55
RAB9A P51151 2/20 0.53
KMT2A Q03164 1/20 0.53
MAOA P21397 3/20 0.53
MAOB P27338 3/20 0.53
FOS P01100 1/20 0.51
JUN P05412 1/20 0.51
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
TP53 P04637 1/20 0.49
THRB P10828 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
POLB P06746 1/20 0.49
APP P05067 1/20 0.47
SLC5A1 P13866 1/20 0.46
SLC5A2 P31639 1/20 0.46
CYP1B1 Q16678 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9302651 1.00 TRPM8 (0.58) TRPM8MAPTRAB9AKMT2AMAOA
SCHEMBL10777127 0.86 TRPM8 (0.55) TRPM8MAPTRAB9AKMT2AMAOA
SCHEMBL2830755 0.84 MAPT (0.54) TRPM8MAPTKMT2AMAOAMAOB
SCHEMBL5677328 0.84 RAB9A (0.58) MAPTRAB9AKMT2AMAOAMAOB
SCHEMBL2830756 0.84 MAPT (0.54) TRPM8MAPTKMT2AMAOAMAOB
SCHEMBL6254356 0.84 F3 (0.68) TRPM8MAPTRAB9AMAOAMAOB
SCHEMBL3398978 0.84 HSD11B1 (0.58) MAPTKMT2AMAOAMAOBTP53
SCHEMBL3398985 0.84 HSD11B1 (0.58) MAPTKMT2AMAOAMAOBTP53
SCHEMBL5677325 0.84 RAB9A (0.58) MAPTRAB9AKMT2AMAOAMAOB
SCHEMBL30819297 0.84 F3 (0.68) TRPM8MAPTRAB9AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024048438-A1 DIASTEREOMER PREPARATION METHOD, AND SOLID-PHASE PHOTOSENSITIZER 学校法人東京理科大学 2024-03-07 WO disclosed
US-5369109-A Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids SAGAMI CHEMICAL RESEARCH CENTER (JP) 1994-11-29 US disclosed
EP-0475627-B1 Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids SAGAMI CHEM RES (JP) 1994-10-19 EP disclosed
US-5276154-A Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids SAGAMI CHEMICAL RESEARCH CENTER (JP) 1994-01-04 US disclosed
EP-0475627-A1 Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-18 EP disclosed