Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268052 | 0.86 | RAB9A (0.66) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL21691150 | 0.85 | RAB9A (0.60) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL3266547 | 0.84 | RAB9A (0.65) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL6031547 | 0.84 | KDM4E (0.79) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL29357142 | 0.84 | KDM4E (0.79) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL10460812 | 0.82 | RAB9A (0.71) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL2485504 | 0.82 | MAPT (0.66) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL2487385 | 0.82 | MAPT (0.66) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL9397239 | 0.82 | RAB9A (0.67) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL334906 | 0.82 | MAPT (0.66) | RAB9AMAPTLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319140-A | Antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5138066-A | Intermediates for cephalosporins with sulfur-containing oxyimino side chain | HOFFMANN-LA ROCHE, INC. (US) | 1992-08-11 | — | — | US | disclosed |
| US-5073550-A | Bactericides | HOFFMANN-LA ROCHE INC. (US) | 1991-12-17 | — | — | US | disclosed |
| US-5036064-A | Antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1991-07-30 | — | — | US | disclosed |