Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 11/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 11/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 11/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301407 | 0.85 | ADRA1D (0.68) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| SCHEMBL9301300 | 0.81 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BL3MBTL1HPGD | |
| SCHEMBL9302313 | 0.79 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| SCHEMBL9302003 | 0.79 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| SCHEMBL9301815 | 0.79 | ADRA1D (0.63) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9302324 | 0.79 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BHPGDTSHR | |
| SCHEMBL9301625 | 0.79 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL7471573 | 0.75 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL8124825 | 0.74 | ADRA1D (0.98) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| SCHEMBL6970869 | 0.74 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |