Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 10/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301300 | 0.91 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| SCHEMBL9302003 | 0.89 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BHPGDSMN1; SMN2 | |
| SCHEMBL9302313 | 0.89 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BHPGDSMN1; SMN2 | |
| SCHEMBL9301815 | 0.87 | ADRA1D (0.63) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9301625 | 0.86 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL9302670 | 0.85 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| SCHEMBL9301424 | 0.81 | ADRA1A (0.45) | ADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7471573 | 0.81 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL8124825 | 0.80 | ADRA1D (0.98) | ADRA1DADRA1AADRA1BHPGDALDH1A1 | |
| SCHEMBL7473727 | 0.77 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |