Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913018 | 1.00 | KMT2A (0.56) | KMT2AMAPTGFERSMN1; SMN2LMNA | |
| SCHEMBL18540053 | 0.93 | THRB (0.49) | KMT2AMAPTGFERSMN1; SMN2NPC1 | |
| SCHEMBL9303970 | 0.92 | MAPT (0.53) | KMT2AMAPTGFERSMN1; SMN2LMNA | |
| SCHEMBL18540075 | 0.91 | THRB (0.47) | KMT2AMAPTGFERSMN1; SMN2NPC1 | |
| SCHEMBL9304788 | 0.91 | MAPT (0.52) | KMT2AMAPTGFERSMN1; SMN2LMNA | |
| SCHEMBL8913348 | 0.89 | THRB (0.61) | KMT2AMAPTGFERSMN1; SMN2NPC1 | |
| SCHEMBL18540255 | 0.88 | THRB (0.45) | KMT2AMAPTGFERSMN1; SMN2RAB9A | |
| SCHEMBL26079702 | 0.86 | SMN1; SMN2 (0.62) | KMT2AMAPTGFERSMN1; SMN2LMNA | |
| SCHEMBL8912760 | 0.86 | THRB (0.58) | KMT2AMAPTSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9303442 | 0.86 | KMT2A (0.49) | KMT2AMAPTSMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304667-A | Cyclosiloxanes containing mesogenic side groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-5221759-A | CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-06-22 | — | — | US | disclosed |