Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303970 | 0.96 | MAPT (0.53) | MAPTGFERKMT2ATHRBSMN1; SMN2 | |
| SCHEMBL9302751 | 0.91 | KMT2A (0.56) | MAPTGFERKMT2ATHRBSMN1; SMN2 | |
| SCHEMBL8913018 | 0.91 | KMT2A (0.56) | MAPTGFERKMT2ATHRBSMN1; SMN2 | |
| SCHEMBL8911968 | 0.90 | THRB (0.60) | MAPTKMT2ATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL8913231 | 0.90 | THRB (0.57) | MAPTKMT2ATHRBSMN1; SMN2NPC1 | |
| SCHEMBL9303608 | 0.87 | THRB (0.47) | MAPTKMT2ATHRBSMN1; SMN2CYP2C9 | |
| SCHEMBL10798412 | 0.87 | THRB (0.64) | MAPTKMT2ATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL10799184 | 0.87 | THRB (0.64) | MAPTKMT2ATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL8923657 | 0.85 | THRB (0.58) | MAPTKMT2ATHRBSMN1; SMN2NPC1 | |
| SCHEMBL8461231 | 0.85 | L3MBTL1 (0.57) | MAPTGFERKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304667-A | Cyclosiloxanes containing mesogenic side groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-5221759-A | CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-06-22 | — | — | US | disclosed |