Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304262 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNAKDM4EMAPK1MEN1 | |
| SCHEMBL9301975 | 0.76 | CYP19A1 (0.54) | — | |
| SCHEMBL578728 | 0.76 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL633906 | 0.76 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL578633 | 0.76 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL5020960 | 0.76 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL579136 | 0.76 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL578832 | 0.76 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL1279062 | 0.76 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL9302327 | 0.75 | POLB (0.56) | ALDH1A1LMNAHTTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |