Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303231 | 0.80 | ALOX5 (0.52) | AKT1ALOX5PPARGPPARAPTGES | |
| SCHEMBL9303654 | 0.80 | AKT1 (0.65) | AKT1ALOX5CYP1A1PTGESPTGS1 | |
| SCHEMBL12713589 | 0.77 | AKT1 (0.58) | AKT1ALOX5PPARGPPARAPTGES | |
| SCHEMBL13009216 | 0.76 | ALOX5 (0.45) | AKT1ALOX5PPARGPPARAPTGES | |
| SCHEMBL16583051 | 0.73 | ALOX5 (0.65) | AKT1ALOX5PPARGPPARAPTGES | |
| SCHEMBL23166882 | 0.72 | ALOX5 (0.48) | ALOX5PSEN1 | |
| SCHEMBL23194701 | 0.72 | ALOX5 (0.48) | ALOX5PSEN1 | |
| SCHEMBL29670779 | 0.72 | ALOX5 (0.48) | ALOX5PSEN1 | |
| SCHEMBL23166880 | 0.72 | ALOX5 (0.48) | ALOX5PSEN1 | |
| SCHEMBL9303437 | 0.72 | ALOX5 (0.58) | AKT1ALOX5PPARGPPARAPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318993-A | Antihyperlipidemic benzoquinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| US-5312929-A | 2-oxo-3-pyrroline derivatives, process for their production and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |