Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713589 | 0.94 | AKT1 (0.58) | AKT1ALOX5PTGESAPP | |
| SCHEMBL13009216 | 0.82 | ALOX5 (0.45) | AKT1ALOX5PTGES | |
| SCHEMBL9302854 | 0.80 | AKT1 (0.43) | AKT1ALOX5PTGESCYP1A1PTGS1 | |
| SCHEMBL15441596 | 0.79 | AKT1 (1.00) | AKT1CYP1A1PDPK1PHLPP1ILK | |
| SCHEMBL9303270 | 0.78 | ALOX5 (0.42) | AKT1ALOX5APP | |
| SCHEMBL12368109 | 0.76 | ALOX5 (0.71) | AKT1ALOX5PTGESPDPK1PHLPP1 | |
| SCHEMBL17523133 | 0.76 | ALOX5 (0.71) | AKT1ALOX5PTGESPDPK1PHLPP1 | |
| SCHEMBL16346022 | 0.75 | AKT1 (0.91) | AKT1PDPK1PHLPP1ILK | |
| SCHEMBL5268822 | 0.75 | AKT1 (0.59) | AKT1PDPK1PHLPP1ILK | |
| SCHEMBL13684464 | 0.73 | ALOX5 (0.54) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318993-A | Antihyperlipidemic benzoquinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-07 | — | — | US | disclosed |