4-Nitroaniline

4-Nitroaniline

SCHEMBL9302985

Nc1ccc([N+](=O)[O-])cc1.O=[N+]([O-])Nc1ccccc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
L3MBTL1 Q9Y468 3/20 0.58
ALOX12 P18054 3/20 0.58
HPGD P15428 1/20 0.58
MEN1 O00255 8/20 0.51
KMT2A Q03164 8/20 0.51
MAPT P10636 6/20 0.51
LMNA P02545 3/20 0.50
GFER P55789 1/20 0.50
CXCR2 P25025 1/20 0.50
CA12 O43570 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
PTPRF P10586 1/20 0.50
PTPN2 P17706 1/20 0.50
PTPN1 P18031 1/20 0.50
PTPN11 Q06124 1/20 0.50
ESR1 P03372 2/20 0.49
CYP19A1 P11511 2/20 0.49
ESR2 Q92731 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL6373876 0.86 ALOX12 (0.79) ALDH1A1L3MBTL1ALOX12HPGDMEN1
Benzene SCHEMBL6151755 0.85 CA9 (0.47) ALDH1A1L3MBTL1ALOX12HPGDMEN1
SCHEMBL4953735 0.81 ALDH1A1 (0.61) ALDH1A1L3MBTL1ALOX12HPGDMEN1
Nitrobenzene SCHEMBL10947937 0.81 ALDH1A1 (0.77) ALDH1A1L3MBTL1ALOX12HPGDMEN1
SCHEMBL45336 0.81 ALDH1A1 (0.50) ALDH1A1L3MBTL1ALOX12MEN1KMT2A
Nitroanilide SCHEMBL6001 0.81 L3MBTL1 (0.50) ALDH1A1L3MBTL1ALOX12HPGDMEN1
Nitroanilide SCHEMBL5718352 0.81 L3MBTL1 (0.50) ALDH1A1L3MBTL1ALOX12HPGDMEN1
Sulfanilamide SCHEMBL27456897 0.80 CA9 (0.55) KMT2AMAPTLMNACA12CA2
SCHEMBL23824900 0.79 CA9 (0.48) ALDH1A1L3MBTL1ALOX12MEN1KMT2A
Nitroanilide SCHEMBL30874122 0.79 ALDH1A1 (0.47) ALDH1A1L3MBTL1ALOX12HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5324648-A Anticoagulants; antitumor agents GEORGIA TECH RESEARCH CORPORATION (US) 1994-06-28 US disclosed