Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22195174 | 1.00 | RIPK1 (0.50) | RIPK1SMN1; SMN2LMNARAB9ACYP1A2 | |
| SCHEMBL21538589 | 0.85 | RIPK1 (0.47) | RIPK1SMN1; SMN2LMNARAB9ACYP1A2 | |
| SCHEMBL24965924 | 0.82 | RIPK1 (0.51) | RIPK1SMN1; SMN2LMNARAB9ACYP1A2 | |
| SCHEMBL1508717 | 0.81 | RIPK1 (0.56) | RIPK1SMN1; SMN2LMNARAB9ACYP1A2 | |
| SCHEMBL2540383 | 0.81 | RIPK1 (0.56) | RIPK1SMN1; SMN2LMNARAB9ACYP1A2 | |
| SCHEMBL1508831 | 0.81 | RIPK1 (0.56) | RIPK1SMN1; SMN2LMNARAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL10481433 | 0.81 | RIPK1 (0.50) | RIPK1SMN1; SMN2LMNARAB9AMMP8 | |
| SCHEMBL4154636 | 0.79 | IDO1 (0.50) | RIPK1SMN1; SMN2LMNARAB9ACYP2D6 | |
| SCHEMBL5431000 | 0.79 | IDO1 (0.50) | RIPK1SMN1; SMN2LMNARAB9ACYP2D6 | |
| SCHEMBL17822177 | 0.79 | LMNA (0.50) | RIPK1SMN1; SMN2LMNARAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324737-A | Analgesics, antirheumatic and antiinflammatory agents, glaucoma | STERLING WINTHROP INC. (US) | 1994-06-28 | — | — | US | disclosed |