SCHEMBL4154636

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5431000	0.86	IDO1 (0.50)	IDO1THRBMAPTCYP3A4KDM4E
	SCHEMBL10703980	0.83	RAB9A (0.50)	IDO1THRBMAPTCYP3A4KDM4E
	SCHEMBL10949413	0.83	SLC6A2 (0.48)	IDO1THRBMAPTCYP3A4KDM4E
	SCHEMBL9482260	0.81	IDO1 (0.61)	IDO1THRBMAPTCYP3A4KDM4E
	SCHEMBL125129	0.81	CYP3A4 (0.52)	IDO1THRBMAPTCYP3A4KDM4E
	SCHEMBL1847644	0.81	RIPK1 (0.51)	IDO1THRBMAPTCYP3A4KDM4E
	SCHEMBL9302997	0.79	RIPK1 (0.50)	IDO1THRBMAPTMEN1KMT2A
	SCHEMBL22195174	0.79	RIPK1 (0.50)	IDO1THRBMAPTMEN1KMT2A
	Bromide SCHEMBL11038149	0.79	CYP3A4 (0.50)	IDO1THRBMAPTCYP3A4KDM4E
	SCHEMBL14145021	0.79	CYP3A4 (0.50)	IDO1THRBMAPTCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.