Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666441 | 0.79 | SMN1; SMN2 (0.42) | KMT2ACYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL80630 | 0.79 | ALDH1A1 (0.36) | KMT2ASMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL22917014 | 0.75 | KMT2A (0.57) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL861034 | 0.71 | KMT2A (0.57) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23839910 | 0.69 | ALDH1A1 (0.58) | KMT2ACYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL23188735 | 0.69 | ALDH1A1 (0.58) | KMT2ACYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL17777241 | 0.69 | ALDH1A1 (0.58) | KMT2ACYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL5663344 | 0.69 | LMNA (0.41) | KMT2ASMN1; SMN2LMNAMEN1TDP1 | |
| SCHEMBL10509488 | 0.69 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL13668152 | 0.69 | KMT2A (0.57) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129159-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110009292-A1 | ATTACHMENT OF MOLECULES TO SURFACES | SURMODICS, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-7829317-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20090042742-A1 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| US-7309593-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2007-12-18 | — | — | US | disclosed |