Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16901802 | 0.80 | ALDH1A1 (0.53) | CHRM2ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL28524361 | 0.80 | ALDH1A1 (0.53) | CHRM2ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL25201803 | 0.80 | ALDH1A1 (0.53) | CHRM2ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL22230787 | 0.80 | ALDH1A1 (0.53) | CHRM2ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL29265122 | 0.78 | ALDH1A1 (0.41) | CHRM2ALDH1A1TSHR | |
| SCHEMBL29265102 | 0.77 | CHRM2 (0.43) | CHRM2ALDH1A1TSHR | |
| SCHEMBL25590610 | 0.77 | CHRM2 (0.83) | CHRM2ALDH1A1TSHRHRH4HRH3 | |
| SCHEMBL17512077 | 0.76 | ACHE (0.47) | ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL14624779 | 0.75 | ALDH1A1 (0.57) | CHRM2ALDH1A1TSHRSMN1; SMN2CYP2D6 | |
| SCHEMBL9305153 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TSHRHRH4HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344974-A | Process for the preparation of N-acyl derivatives of 5-aminolevulinic acid, as well as the hydrochloride of the free acid | SUDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHENSFURT (DE) | 1994-09-06 | — | — | US | claimed |
| EP-0584585-A1 | Process for the preparation of N-acylderivatives of the acid 5-aminolevulinic and their hydrochlorides | SÜDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT (DE) | 1994-03-02 | — | — | EP | claimed |
| JP-6172281-A | — | — | None | — | — | JP | disclosed |
| US-5344974-A | Process for the preparation of N-acyl derivatives of 5-aminolevulinic acid, as well as the hydrochloride of the free acid | SUDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHENSFURT (DE) | 1994-09-06 | — | — | US | disclosed |
| JP-H06172281-A | PREPARATION OF N-ACYL DERIVATIVE OF 5-AMINOLEVULINIC ACID AS WELL AS HYDROCHLORIDE OF FREE ACID OF THE SAME | SUEDZUCKER AG MANNHEIM OCHSENFURT | 1994-06-21 | — | — | JP | disclosed |
| EP-0584585-A1 | Process for the preparation of N-acylderivatives of the acid 5-aminolevulinic and their hydrochlorides | SÜDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT (DE) | 1994-03-02 | — | — | EP | disclosed |