SCHEMBL16901802

SCHEMBL16901802

CCCCCCc1ccc(C=O)o1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TSHR P16473 1/20 0.53
EPHX2 P34913 1/20 0.51
HIF1A Q16665 2/20 0.45
EPAS1 Q99814 1/20 0.45
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPT P10636 2/20 0.43
ALOX5 P09917 2/20 0.41
PTGS1 P23219 2/20 0.41
PTGS2 P35354 2/20 0.41
GAA P10253 1/20 0.40
GPR84 Q9NQS5 1/20 0.39
ALOX15 P16050 1/20 0.38
ELANE P08246 3/20 0.37
DNMT1 P26358 1/20 0.37
NPC1 O15118 1/20 0.36
STAT1 P42224 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25201803 1.00 ALDH1A1 (0.53) ALDH1A1TSHREPHX2HIF1AEPAS1
SCHEMBL2903199 1.00 ALDH1A1 (0.53) ALDH1A1TSHREPHX2HIF1AEPAS1
SCHEMBL22230787 1.00 ALDH1A1 (0.53) ALDH1A1TSHREPHX2HIF1AEPAS1
SCHEMBL28524361 1.00 ALDH1A1 (0.53) ALDH1A1TSHREPHX2HIF1AEPAS1
SCHEMBL625752 0.98 ALDH1A1 (0.55) ALDH1A1TSHREPHX2HIF1AEPAS1
SCHEMBL8635202 0.92 ALDH1A1 (0.57) ALDH1A1TSHREPHX2HIF1AEPAS1
SCHEMBL16806596 0.90 ALOX5 (0.50) ALDH1A1TSHREPHX2HIF1AEPAS1
SCHEMBL8640022 0.84 ALDH1A1 (0.61) ALDH1A1TSHREPHX2HTTL3MBTL1
SCHEMBL10878735 0.82 EPHX2 (0.57) ALDH1A1EPHX2HIF1AMAPTALOX5
SCHEMBL3924849 0.82 EPHX2 (0.57) ALDH1A1EPHX2HIF1AMAPTALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037531-B2 Photoresponsive high-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2024-07-16 US disclosed
CN-111560090-A Photoresponsive polymer material, adhesive, toner and image forming method 柯尼卡美能达株式会社 2020-08-21 CN disclosed
US-20200263088-A1 PHOTORESPONSIVE HIGH-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2020-08-20 US disclosed
EP-3696200-A1 PHOTORESPONSIVE HIGH-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD KONICA MINOLTA, INC. (JP) 2020-08-19 EP disclosed
EP-2861570-B1 ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES UNIV RUTGERS (US) 2018-07-18 EP disclosed
US-9592221-B2 Antibacterial agents: aryl myxopyronin derivatives RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-03-14 US disclosed
US-9592221-B2 Antibacterial agents: aryl myxopyronin derivatives RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-03-14 US disclosed
US-20160263083-A1 ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-09-15 US disclosed
US-20160263083-A1 ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-09-15 US disclosed
US-9315495-B2 Antibacterial agents: aryl myxopyronin derivatives RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-04-19 US disclosed
US-9315495-B2 Antibacterial agents: aryl myxopyronin derivatives RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-04-19 US disclosed
US-20150197512-A1 ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES PROVID PHARMACEUTICALS INC. 2015-07-16 US disclosed
US-20150197512-A1 ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES PROVID PHARMACEUTICALS INC. 2015-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160263083-A1 ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES POLRMT, POLR1C, FBL ALDH1A1 1785/4885TSHR 3518/4885EPHX2 2958/4885
US-20150197512-A1 ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES FBL, POLRMT, POLR1C ALDH1A1 1561/4885TSHR 3104/4885EPHX2 3318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.