Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304069 | 0.87 | DHODH (0.50) | KMT2AMEN1PKMMAPTCTSK | |
| Benzene SCHEMBL27690342 | 0.84 | KMT2A (0.57) | KMT2AMEN1PKMMAPTCTSK | |
| SCHEMBL233797 | 0.84 | KMT2A (0.57) | KMT2AMEN1PKMMAPTCTSK | |
| Hydrochloric Acid SCHEMBL6013658 | 0.82 | KMT2A (0.55) | KMT2AMEN1PKMMAPTCTSK | |
| SCHEMBL9302227 | 0.81 | KMT2A (0.49) | KMT2AMEN1PKMMAPTCTSK | |
| SCHEMBL9303020 | 0.78 | NR1H4 (0.53) | SIRT2PLAUPRSS1 | |
| 4-Guanidino-Benzoic Acid SCHEMBL9304265 | 0.78 | MEN1 (0.56) | KMT2AMEN1PLAUPRSS1PRSS2 | |
| SCHEMBL9303029 | 0.78 | PARP1 (0.52) | KMT2AMEN1PKMPLAU | |
| SCHEMBL2850803 | 0.77 | PARP1 (0.59) | PKMMAPTPOLBPRSS1PRSS2 | |
| SCHEMBL7902232 | 0.77 | KMT2A (0.50) | KMT2AMEN1PKMMAPTCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |