Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 10/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | PLAT | P00750 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303522 | 0.86 | PLAU (0.61) | NR1H4RXFP1PLAUF2PLG | |
| SCHEMBL9303229 | 0.85 | PLAU (0.56) | NR1H4RXFP1PLAUF2PLG | |
| SCHEMBL9304086 | 0.85 | PLAU (0.69) | SIRT2PLAUF2PLGPLAT | |
| SCHEMBL9304048 | 0.84 | SIRT2 (0.55) | NR1H4SIRT2RXFP1PLAUF2 | |
| SCHEMBL9303041 | 0.83 | PLAU (0.61) | RXFP1PLAUF2PLGPLAT | |
| Hydrochloric Acid SCHEMBL6542009 | 0.82 | NR1H4 (0.78) | NR1H4RXFP1 | |
| SCHEMBL15528622 | 0.81 | RXFP1 (0.67) | RXFP1PLAUKLK1 | |
| SCHEMBL9303274 | 0.81 | PLAU (0.62) | PLAUF2PLGPLATF10 | |
| SCHEMBL9302799 | 0.81 | RXFP1 (0.50) | NR1H4RXFP1PLAUF2PLG | |
| SCHEMBL7661381 | 0.80 | LMNA (0.65) | PLAUF2PLATF10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |