Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593555 | 0.87 | NR5A1 (0.46) | GAAESR1LMNACYP1A2CYP2D6 | |
| SCHEMBL29444204 | 0.87 | ESR1 (0.36) | POLBGAAESR1ESR2LMNA | |
| SCHEMBL11459792 | 0.86 | ESR1 (0.38) | GAAESR1ESR2LMNACYP1A2 | |
| SCHEMBL9862024 | 0.82 | GAA (0.43) | GAAESR1LMNACYP1A2CYP2D6 | |
| SCHEMBL3234995 | 0.81 | FDPS (0.46) | ESR1ESR2LMNACYP1A2CYP2D6 | |
| SCHEMBL5664826 | 0.80 | POLB (0.44) | POLBGAAESR1ESR2LMNA | |
| SCHEMBL5664657 | 0.77 | POLB (0.50) | POLBGAAESR1ESR2LMNA | |
| SCHEMBL23357363 | 0.77 | PTPN2 (0.50) | POLBGAALMNAMAPTTSHR | |
| SCHEMBL27794142 | 0.77 | ESR1 (0.36) | POLBGAAESR1ESR2LMNA | |
| SCHEMBL9303065 | 0.74 | ESR1 (0.37) | ESR1ESR2LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372924-A | Plastic support, first layer containing polythiophene and second layer containing prepolymer curable by exposure to ionizing radiation | AGFA GEVAERT AKTIENGESELLSCHAFT (DE) | 1994-12-13 | — | — | US | disclosed |
| US-4387170-A | Process for the production of foamed materials from polyolefins | DYNAMIT NOBEL AG (DE) | 1983-06-07 | — | — | US | disclosed |
| US-4076690-A | 3-CHLORO-5-ALKYL-4-HYDROXYPHENYL(ALKYL)PHOSPHONATES | CIBA-GEIGY CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |