Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444204 | 0.82 | ESR1 (0.36) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3234995 | 0.79 | FDPS (0.46) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11459792 | 0.76 | ESR1 (0.38) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1836347 | 0.74 | SMN1; SMN2 (0.39) | LMNACYP1A2MAPTALOX15SMN1; SMN2 | |
| SCHEMBL1961626 | 0.74 | ALDH1A1 (0.39) | LMNASMN1; SMN2 | |
| SCHEMBL9303060 | 0.74 | POLB (0.43) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1837400 | 0.74 | ACP3 (0.44) | LMNA | |
| SCHEMBL10555914 | 0.73 | SMPD1 (0.44) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27750179 | 0.71 | SMPD1 (0.39) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27750183 | 0.71 | ESR1 (0.41) | ESR1LMNACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372924-A | Plastic support, first layer containing polythiophene and second layer containing prepolymer curable by exposure to ionizing radiation | AGFA GEVAERT AKTIENGESELLSCHAFT (DE) | 1994-12-13 | — | — | US | disclosed |