Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 6/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302839 | 0.88 | HDAC1 (0.67) | HRH3KMT2AIDO1HDAC1HDAC6 | |
| SCHEMBL1751266 | 0.84 | IDO1 (0.53) | HRH3IDO1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL2885662 | 0.81 | CYP11B1 (0.67) | HRH3IDO1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL19421681 | 0.81 | CDK9 (0.46) | FAAHMGLLHRH3MEN1KMT2A | |
| SCHEMBL19421686 | 0.80 | CDK9 (0.46) | FAAHMGLLHRH3MEN1KMT2A | |
| SCHEMBL7662930 | 0.77 | CYP11B1 (0.58) | HRH3IDO1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL13085846 | 0.77 | IDO1 (0.64) | HRH3IDO1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL19421697 | 0.75 | CDK9 (0.44) | — | |
| SCHEMBL13085754 | 0.74 | HRH3 (0.76) | HRH3IDO1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL31722842 | 0.74 | CYP11B1 (0.80) | MEN1KMT2AIDO1ALDH1A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |