SCHEMBL9303342

SCHEMBL9303342

CCCCCCCCCCCCCCCCCC(F)CCCCCCCS(=O)(=O)c1ccc(NN2C(=O)CCCC2=O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.38
THRA P10827 1/20 0.35
POLB P06746 2/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NR1I2 O75469 1/20 0.34
PLA2G2C Q5R387 1/20 0.33
CYP2C19 P33261 2/20 0.32
MMP13 P45452 1/20 0.32
MCHR1 Q99705 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9305422 0.86 THRB (0.37) THRBTHRANR1I2PLA2G2CCYP2C19
SCHEMBL9303466 0.78 THRB (0.41) THRBTHRAKMT2ANR1I2PLA2G2C
SCHEMBL9693132 0.73 CRBN (0.49)
SCHEMBL9520362 0.71 THRB (0.41) THRBTHRANR1I2PLA2G2CCYP2C19
SCHEMBL9017375 0.67 THRB (0.49) THRBTHRAPOLBKMT2ACYP2C19
SCHEMBL28447913 0.65 NR1I2 (0.55) THRBTHRANR1I2CYP2C19MMP13
SCHEMBL28452673 0.65 NR1I2 (0.55) THRBTHRANR1I2CYP2C19MMP13
SCHEMBL14379397 0.65 PLCG1 (0.59) THRBTHRAPOLBKMT2ACYP2C19
SCHEMBL8164968 0.65 ALDH1A1 (0.65) THRBTHRAPOLBKMT2ACYP2C19
SCHEMBL10300267 0.64 THRB (0.55) THRBTHRACYP2C19MMP13MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546113-A1 NONLINEAR OPTICAL MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-16 EP claimed
US-5312565-A Nonlinear optical materials E. I. DUPONT DE NEMOURS AND COMPANY (US) 1994-05-17 US disclosed
EP-0546113-A1 NONLINEAR OPTICAL MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-16 EP disclosed
WO-1992003417-A2 NONLINEAR OPTICAL MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-05 WO disclosed