Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787104 | 0.90 | DRD2 (0.56) | DRD2DRD4DRD3HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL9787054 | 0.88 | DRD2 (0.55) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL9306055 | 0.88 | DRD2 (0.47) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL9306865 | 0.84 | DRD2 (0.51) | DRD2DRD4DRD3HTR1AMEN1 | |
| SCHEMBL9304332 | 0.81 | DRD2 (0.48) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL3386360 | 0.79 | HTR1A (0.49) | DRD2DRD4DRD3HTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL9787141 | 0.78 | HTR1A (0.48) | DRD2DRD4DRD3HTR1ACYP1A2 | |
| SCHEMBL9824766 | 0.78 | HTR1A (0.54) | DRD2DRD4DRD3HTR1ACYP1A2 | |
| SCHEMBL9083462 | 0.78 | HTR1A (0.60) | DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9787193 | 0.77 | HTR1A (0.53) | DRD2DRD4DRD3HTR1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346916-A | FOR TREATING ANIMALS SUFFERING FROM DISORDERS OF THE SEROTONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1994-09-13 | — | — | US | disclosed |
| US-5314907-A | 3-aminochroan compounds | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| US-5273994-A | Also hydroxy- or alkyl ether-substituted | ADIR ET COMPAGNIE (FR) | 1993-12-28 | — | — | US | disclosed |