Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787104 | 0.94 | DRD2 (0.56) | DRD2DRD4DRD3HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL9787054 | 0.93 | DRD2 (0.55) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL9304332 | 0.92 | DRD2 (0.48) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL9303497 | 0.84 | DRD2 (0.46) | DRD2DRD4DRD3HTR1AMEN1 | |
| SCHEMBL9306055 | 0.84 | DRD2 (0.47) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL3386360 | 0.83 | HTR1A (0.49) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL9824766 | 0.82 | HTR1A (0.54) | DRD2DRD4DRD3HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL9787141 | 0.82 | HTR1A (0.48) | DRD2DRD4DRD3HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL9787193 | 0.81 | HTR1A (0.53) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL8874827 | 0.80 | FYN (0.45) | DRD2DRD3HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346916-A | FOR TREATING ANIMALS SUFFERING FROM DISORDERS OF THE SEROTONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1994-09-13 | — | — | US | disclosed |
| US-5314907-A | 3-aminochroan compounds | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| US-5273994-A | Also hydroxy- or alkyl ether-substituted | ADIR ET COMPAGNIE (FR) | 1993-12-28 | — | — | US | disclosed |
| US-5252578-A | Treatment of disorders of teh serotoninergic system | ADIR ET COMPAGNIE (FR) | 1993-10-12 | — | — | US | disclosed |