Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 17/20 | 0.61 |
| ▸ | PLG | P00747 | 10/20 | 0.60 |
| ▸ | F2 | P00734 | 8/20 | 0.60 |
| ▸ | PLAT | P00750 | 8/20 | 0.60 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.60 |
| ▸ | KLK1 | P06870 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303229 | 0.96 | PLAU (0.56) | PLAUPLGF2PLATKLKB1 | |
| SCHEMBL9304086 | 0.87 | PLAU (0.69) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL9303020 | 0.86 | NR1H4 (0.53) | PLAUPLGF2PLATKLKB1 | |
| SCHEMBL9303274 | 0.82 | PLAU (0.62) | PLAUPLGF2PLATKLKB1 | |
| SCHEMBL9302799 | 0.82 | RXFP1 (0.50) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL9303292 | 0.81 | RXFP1 (0.52) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL9303523 | 0.81 | NPC1 (0.53) | PLAUPLGF2PLATKLKB1 | |
| SCHEMBL9303344 | 0.81 | PLAU (0.74) | PLAUPLGF2PLATKLKB1 | |
| SCHEMBL7335930 | 0.81 | PLAU (0.78) | PLAUPLGF2PLATKLKB1 | |
| SCHEMBL5566603 | 0.81 | PLAU (0.78) | PLAUPLGF2PLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |