Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 9/20 | 0.69 |
| ▸ | PLAT | P00750 | 9/20 | 0.69 |
| ▸ | F2 | P00734 | 9/20 | 0.69 |
| ▸ | F10 | P00742 | 9/20 | 0.69 |
| ▸ | PLG | P00747 | 5/20 | 0.69 |
| ▸ | KLK1 | P06870 | 5/20 | 0.63 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.54 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.54 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303522 | 0.87 | PLAU (0.61) | PLAUPLATF2F10PLG | |
| SCHEMBL9303229 | 0.86 | PLAU (0.56) | PLAUPLATF2F10PLG | |
| SCHEMBL9303020 | 0.85 | NR1H4 (0.53) | PLAUPLATF2F10PLG | |
| SCHEMBL9302237 | 0.83 | F10 (0.49) | PLAUPLATF2F10PLG | |
| SCHEMBL9303615 | 0.82 | PDCD1 (0.55) | PLAUPLATF2F10PLG | |
| SCHEMBL7244941 | 0.82 | PLAU (1.00) | PLAUPLATF2F10PLG | |
| SCHEMBL9304069 | 0.79 | DHODH (0.50) | PLAUPLATF2F10PLG | |
| SCHEMBL9303338 | 0.79 | F2 (0.67) | PLAUPLATF2F10PLG | |
| SCHEMBL9302799 | 0.79 | RXFP1 (0.50) | PLAUPLATF2F10PLG | |
| SCHEMBL9303274 | 0.79 | PLAU (0.62) | PLAUPLATF2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |