Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PLAU | P00749 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | PLAT | P00750 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303292 | 0.91 | RXFP1 (0.52) | RXFP1DEGS1MEN1KMT2APLAU | |
| SCHEMBL9303115 | 0.84 | PLAU (0.53) | MEN1KMT2APLAUNPC1RAB9A | |
| SCHEMBL9303522 | 0.82 | PLAU (0.61) | RXFP1PLAUKLK1PLGF2 | |
| SCHEMBL9304321 | 0.82 | PLAU (0.50) | MEN1KMT2APLAUNPC1RAB9A | |
| SCHEMBL9302832 | 0.82 | RXFP1 (0.50) | RXFP1DEGS1MEN1KMT2APLAU | |
| SCHEMBL9303229 | 0.81 | PLAU (0.56) | RXFP1MEN1KMT2APLAUNPC1 | |
| SCHEMBL9303020 | 0.81 | NR1H4 (0.53) | RXFP1PLAUKLK1PTGESPLG | |
| SCHEMBL9302787 | 0.81 | PLAU (0.45) | DEGS1MEN1KMT2APLAUNPC1 | |
| SCHEMBL9303445 | 0.80 | NPC1 (0.54) | RXFP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9303274 | 0.80 | PLAU (0.62) | PLAUNPC1RAB9AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |