Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PLAU | P00749 | 8/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302787 | 0.92 | PLAU (0.45) | DEGS1TMPRSS2NPC1RAB9AMEN1 | |
| SCHEMBL9304147 | 0.89 | DEGS1 (0.44) | DEGS1TMPRSS2NPC1RAB9AHDAC1 | |
| SCHEMBL9303517 | 0.82 | PLAU (0.58) | NPC1RAB9AMEN1KMT2APLAU | |
| SCHEMBL9304170 | 0.81 | PLAU (0.54) | NPC1RAB9AMEN1KMT2APLAU | |
| SCHEMBL9303292 | 0.81 | RXFP1 (0.52) | DEGS1TMPRSS2NPC1RAB9AHDAC1 | |
| SCHEMBL9303518 | 0.80 | NPC1 (0.49) | NPC1RAB9APLAUKLK1KLK5 | |
| SCHEMBL9303484 | 0.78 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2APLAU | |
| SCHEMBL9303218 | 0.78 | PLAU (0.44) | NPC1RAB9APLAUKLK1KLK5 | |
| SCHEMBL9303554 | 0.78 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2APLAU | |
| SCHEMBL9303967 | 0.77 | KCNJ11 (0.43) | DEGS1NPC1RAB9APLAUKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |