Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 12/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | PLG | P00747 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PLAT | P00750 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 3/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303554 | 0.85 | NPC1 (0.46) | PLAUNPC1RAB9AKDM4EMAPT | |
| SCHEMBL9303439 | 0.81 | NPC1 (0.45) | PLAUF10PLGF2PLAT | |
| SCHEMBL9303221 | 0.80 | NPC1 (0.46) | PLAUF10PLGF2PLAT | |
| SCHEMBL9303327 | 0.80 | RAB9A (0.44) | PLAUNPC1RAB9AGFERKDM4E | |
| SCHEMBL9303532 | 0.80 | PLAU (0.57) | PLAUPLGF2PLATNPC1 | |
| SCHEMBL9303612 | 0.80 | NPC1 (0.43) | PLAUF10PLGF2PLAT | |
| SCHEMBL9303484 | 0.80 | NPC1 (0.49) | PLAUNPC1RAB9AKDM4EMAPT | |
| SCHEMBL9302787 | 0.79 | PLAU (0.45) | PLAUF10PLGF2PLAT | |
| SCHEMBL9304147 | 0.79 | DEGS1 (0.44) | PLAUF10PLGF2PLAT | |
| SCHEMBL9303518 | 0.79 | NPC1 (0.49) | PLAUPLGF2PLATNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |