Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303532 | 0.92 | PLAU (0.57) | NPC1RAB9APLAUHSD17B10CHRNB2 | |
| SCHEMBL9303439 | 0.89 | NPC1 (0.45) | NPC1RAB9APLAUHSD17B10CHRNB2 | |
| SCHEMBL9303523 | 0.84 | NPC1 (0.53) | NPC1RAB9APLAUHSD17B10CHRNB2 | |
| SCHEMBL9303484 | 0.81 | NPC1 (0.49) | NPC1RAB9APLAUHSD17B10CHRNB2 | |
| SCHEMBL9303554 | 0.81 | NPC1 (0.46) | NPC1RAB9APLAUCHRNB2CHRNB4 | |
| SCHEMBL9303517 | 0.81 | PLAU (0.58) | NPC1RAB9APLAUKLK1KLK5 | |
| SCHEMBL9303538 | 0.80 | DEGS1 (0.46) | NPC1RAB9APLAUKLK1KLK5 | |
| SCHEMBL9304170 | 0.80 | PLAU (0.54) | NPC1RAB9APLAUKLK1KLK5 | |
| SCHEMBL9303218 | 0.79 | PLAU (0.44) | NPC1RAB9APLAUKDM4ESMN1; SMN2 | |
| SCHEMBL9303327 | 0.77 | RAB9A (0.44) | NPC1RAB9APLAUCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |