Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 18/20 | 0.58 |
| ▸ | PLG | P00747 | 11/20 | 0.57 |
| ▸ | PLAT | P00750 | 9/20 | 0.57 |
| ▸ | F2 | P00734 | 8/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | KLK1 | P06870 | 3/20 | 0.57 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304170 | 0.96 | PLAU (0.54) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9302787 | 0.83 | PLAU (0.45) | PLAUPLGPLATF2KLK1 | |
| SCHEMBL9303538 | 0.82 | DEGS1 (0.46) | PLAUPLGPLATF2KLK1 | |
| SCHEMBL9303532 | 0.81 | PLAU (0.57) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9303522 | 0.81 | PLAU (0.61) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9303518 | 0.81 | NPC1 (0.49) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL5566603 | 0.79 | PLAU (0.78) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL7335930 | 0.79 | PLAU (0.78) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9304147 | 0.79 | DEGS1 (0.44) | PLAUPLGPLATF2F10 | |
| SCHEMBL9303439 | 0.78 | NPC1 (0.45) | PLAUPLGPLATF2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |