Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571095 | 0.68 | POLB (0.37) | ALDH1A1KMT2APOLBKDM4ELMNA | |
| SCHEMBL19663105 | 0.65 | — | — | |
| SCHEMBL18287701 | 0.65 | ALDH1A1 (0.37) | ALDH1A1KMT2APOLBKDM4ELMNA | |
| SCHEMBL531260 | 0.65 | LMNA (0.31) | LMNA | |
| SCHEMBL4713118 | 0.65 | POLB (0.34) | ALDH1A1KMT2APOLBKDM4ELMNA | |
| SCHEMBL1133003 | 0.65 | TDP1 (0.34) | ALDH1A1POLBKDM4ELMNAMAPT | |
| SCHEMBL10028031 | 0.65 | LMNA (0.36) | ALDH1A1LMNA | |
| Cyclopropane SCHEMBL17923269 | 0.64 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL7603692 | 0.64 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL37684 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326887-A | Reacting ester of alpha hydroxy acid oligomer over fixed bed catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1992015572-A1 | PROCESS FOR THE PREPARATION OF 1,4-DIOXANE-2,5-DIONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |