Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809822 | 0.84 | CHRM5 (0.49) | CHRM5CHRM3SIGMAR1EGFR | |
| SCHEMBL6826228 | 0.79 | SIGMAR1 (0.48) | CHRM5CHRM3SIGMAR1EGFR | |
| SCHEMBL10762752 | 0.68 | CHRM5 (0.44) | CHRM5CHRM3SIGMAR1EGFR | |
| Hydrochloric Acid SCHEMBL27785421 | 0.67 | TDP1 (0.52) | — | |
| SCHEMBL24247411 | 0.66 | CHRM5 (0.55) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL8038 | 0.66 | CHRM5 (0.55) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL1126801 | 0.66 | CHRM5 (0.46) | CHRM5CHRM3SIGMAR1EGFR | |
| Methacrylic Acid SCHEMBL28258699 | 0.66 | BBOX1 (0.34) | — | |
| Acetic Acid SCHEMBL10901374 | 0.66 | CHRM5 (0.40) | CHRM5CHRM3SIGMAR1 | |
| Acetic Acid SCHEMBL367270 | 0.66 | BBOX1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5320711-A | Modified with glyoxal to crosslink, having specific diameters; wet and dry strength | CYTEC TECHNOLOGY CORP. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5041503-A | Inverse microemulsion polymerization; wet and dry-strength agents for paper | AMERICAN CYANAMID COMPANY (US) | 1991-08-20 | — | — | US | disclosed |