Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546855 | 1.00 | PRMT5 (0.44) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL10500771 | 0.84 | PRMT5 (0.60) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL4658490 | 0.84 | PRMT5 (0.60) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL3901109 | 0.84 | PRMT5 (0.60) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL9303799 | 0.81 | PRMT5 (0.53) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL9303794 | 0.81 | PRMT5 (0.53) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL7537706 | 0.80 | LMNA (0.47) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL9304971 | 0.79 | PRMT5 (0.74) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL9304964 | 0.79 | PRMT5 (0.74) | PRMT5WDR77ACHEKMT2AMEN1 | |
| SCHEMBL9305032 | 0.74 | ALDH1A1 (0.48) | PRMT5WDR77KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326885-A | Process of preparing enriched enantiomers of glycerol carbonate and derivatives thereof for synthesis of β-blockers | COGNIS, INC. (US) | 1994-07-05 | — | — | US | disclosed |