Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303580 | 0.82 | MAPK1 (0.56) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL9302647 | 0.81 | MAPK1 (0.55) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL9302744 | 0.78 | MEN1 (0.52) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL9304089 | 0.78 | MEN1 (0.52) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL9305955 | 0.77 | HTR2A (0.59) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL9304934 | 0.74 | HTR2A (0.55) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL17686297 | 0.69 | MCL1 (0.52) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL9303008 | 0.68 | MCL1 (0.54) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL17686287 | 0.66 | MCL1 (0.63) | KMT2AMEN1MAPK1HTR2AHTR2C | |
| SCHEMBL8557902 | 0.65 | KMT2A (0.45) | KMT2AMEN1MAPK1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |