Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9303560 | 0.98 | ALDH1A1 (0.45) | TSHRALDH1A1AOC3RIPK1CARM1 | |
| SCHEMBL9303465 | 0.81 | TSHR (0.47) | TSHRALDH1A1AOC3RIPK1CARM1 | |
| SCHEMBL19954207 | 0.79 | TSHR (0.52) | TSHRALDH1A1AOC3RIPK1CARM1 | |
| SCHEMBL1640061 | 0.76 | TSHR (0.58) | TSHRALDH1A1AOC3RIPK1CARM1 | |
| SCHEMBL9426376 | 0.73 | DRD2 (0.56) | TSHRALDH1A1CYP2C19RAB9ACYP3A4 | |
| SCHEMBL11249019 | 0.72 | TSHR (0.54) | TSHRALDH1A1AOC3RIPK1CARM1 | |
| SCHEMBL27258851 | 0.72 | TSHR (0.54) | TSHRALDH1A1AOC3RIPK1CARM1 | |
| SCHEMBL20844585 | 0.72 | AOC3 (0.56) | TSHRALDH1A1AOC3RIPK1CARM1 | |
| Chloromethane SCHEMBL28157121 | 0.71 | TSHR (0.90) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL31481619 | 0.70 | TSHR (0.56) | TSHRALDH1A1AOC3RIPK1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505379-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-5302595-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |
| US-5219871-A | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1993-06-15 | — | — | US | disclosed |
| WO-1991009014-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-06-27 | — | — | WO | disclosed |
| EP-0364123-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0364123-A1 | Muscarinic receptor antagonists | Pfizer Limited (GB) | 1990-04-18 | — | — | EP | disclosed |