Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.47 |
| ▸ | CA1 | P00915 | 14/20 | 0.45 |
| ▸ | CA9 | Q16790 | 10/20 | 0.45 |
| ▸ | CA12 | O43570 | 8/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.45 |
| ▸ | CA4 | P22748 | 8/20 | 0.44 |
| ▸ | CA7 | P43166 | 8/20 | 0.44 |
| ▸ | CA5A | P35218 | 5/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.44 |
| ▸ | CA6 | P23280 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302028 | 0.77 | CA12 (0.52) | CA9CA12MAPTSMN1; SMN2 | |
| SCHEMBL9302642 | 0.76 | ALDH1A1 (0.54) | MAPTKDM4E | |
| SCHEMBL9260114 | 0.75 | TSHR (0.41) | MAPTSMN1; SMN2KDM4E | |
| SCHEMBL9302598 | 0.75 | NR1H3 (0.50) | MAPT | |
| SCHEMBL9302515 | 0.74 | ALDH1A1 (0.44) | SMN1; SMN2KDM4E | |
| SCHEMBL9303752 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4E | |
| SCHEMBL9303789 | 0.74 | ESR1 (0.56) | MAPT | |
| SCHEMBL9302813 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2KDM4E | |
| SCHEMBL9302837 | 0.74 | ALDH1A1 (0.59) | MAPTSMN1; SMN2KDM4E | |
| SCHEMBL9302302 | 0.74 | CXCR4 (0.48) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |