Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 7/20 | 0.52 |
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302642 | 0.85 | ALDH1A1 (0.54) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9302028 | 0.84 | CA12 (0.52) | HTTPGRALDH1A1LMNANR1I2 | |
| SCHEMBL9302598 | 0.81 | NR1H3 (0.50) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9302843 | 0.81 | CNR2 (0.62) | CNR2GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL9302737 | 0.77 | CXCR4 (0.46) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9302302 | 0.77 | CXCR4 (0.48) | CNR2CNR1HTTALDH1A1LMNA | |
| SCHEMBL5330652 | 0.77 | ESR1 (0.78) | ESR1CNR2CNR1GAAHTT | |
| SCHEMBL9303870 | 0.74 | CA2 (0.47) | MAPT | |
| SCHEMBL9303027 | 0.74 | CXCR4 (0.45) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9302515 | 0.73 | ALDH1A1 (0.44) | ESR1CNR2CNR1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |